| 1 |  St. Louis City | 15 | 10 | 5 | 0 | 35:18 | +17 | 35 | ?Next matchNew York Red Bulls – St. Louis CitySep 26, 11:30 PM DDrawSt. Louis City 3–3 FC DallasAug 30, 11:00 PM WWinVancouver Whitecaps 1–3 St. Louis CitySep 06, 02:30 AM DDrawPortland Timbers 2–2 St. Louis CitySep 10, 02:30 AM WWinSt. Louis City 4–2 Minnesota United FCSep 13, 12:30 AM WWinSt. Louis City 3–1 Toronto FCSep 20, 12:30 AM |
| 2 |  Nashville SC | 15 | 10 | 3 | 2 | 30:13 | +17 | 33 | ?Next matchNashville SC – Toronto FCSep 27, 12:30 AM WWinNashville SC 4–0 FC CincinnatiAug 30, 12:30 AM DDrawNew York City FC 0–0 Nashville SCSep 04, 11:30 PM LLossToronto FC 2–1 Nashville SCSep 09, 11:30 PM DDrawInter Miami 2–2 Nashville SCSep 12, 11:30 PM WWinNashville SC 3–0 Chicago FireSep 20, 01:30 AM |
| 3 |  Philadelphia Union | 15 | 9 | 3 | 3 | 41:25 | +16 | 30 | ?Next matchPhiladelphia Union – Orlando City SCSep 26, 11:30 PM WWinNew York Red Bulls 1–3 Philadelphia UnionAug 29, 11:30 PM WWinPhiladelphia Union 2–0 CF MontrealSep 05, 11:30 PM WWinPhiladelphia Union 5–0 FC CincinnatiSep 09, 11:45 PM WWinSan Diego 0–5 Philadelphia UnionSep 14, 01:00 AM WWinSporting Kansas City 3–4 Philadelphia UnionSep 20, 12:30 AM |
| 4 |  Charlotte | 15 | 8 | 5 | 2 | 29:18 | +11 | 29 | ?Next matchCharlotte – Chicago FireSep 26, 11:30 PM WWinAtlanta United FC 0–2 CharlotteAug 29, 11:30 PM DDrawCharlotte 0–0 Houston DynamoSep 05, 11:30 PM WWinCF Montreal 1–2 CharlotteSep 09, 11:30 PM DDrawFC Cincinnati 3–3 CharlotteSep 12, 11:30 PM WWinDC United 1–2 CharlotteSep 19, 11:30 PM |
| 5 |  FC Dallas | 15 | 8 | 4 | 3 | 29:27 | +2 | 28 | ?Next matchFC Dallas – Los Angeles FCSep 27, 12:30 AM DDrawSt. Louis City 3–3 FC DallasAug 30, 11:00 PM WWinFC Dallas 4–3 Sporting Kansas CitySep 06, 12:30 AM WWinMinnesota United FC 1–2 FC DallasSep 10, 12:30 AM WWinFC Dallas 2–1 Portland TimbersSep 13, 12:30 AM DDrawFC Dallas 0–0 AustinSep 20, 12:30 AM |
| 6 |  Inter Miami | 15 | 7 | 6 | 2 | 41:29 | +12 | 27 | ?Next matchColumbus Crew – Inter MiamiSep 27, 11:00 PM WWinInter Miami 7–1 CF MontrealAug 29, 11:30 PM DDrawInter Miami 2–2 Atlanta United FCSep 05, 11:30 PM DDrawChicago Fire 1–1 Inter MiamiSep 10, 12:30 AM DDrawInter Miami 2–2 Nashville SCSep 12, 11:30 PM DDrawInter Miami 2–2 San DiegoSep 20, 11:00 PM |
| 7 |  Houston Dynamo | 15 | 7 | 5 | 3 | 17:11 | +6 | 26 | ?Next matchHouston Dynamo – Sporting Kansas CitySep 27, 12:30 AM DDrawHouston Dynamo 0–0 San Jose EarthquakesAug 30, 12:30 AM DDrawCharlotte 0–0 Houston DynamoSep 05, 11:30 PM WWinHouston Dynamo 2–1 Real Salt LakeSep 10, 12:30 AM LLossSan Jose Earthquakes 1–0 Houston DynamoSep 13, 02:30 AM DDrawHouston Dynamo 2–2 FC CincinnatiSep 20, 12:30 AM |
| 8 |  Vancouver Whitecaps | 15 | 7 | 3 | 5 | 30:17 | +13 | 24 | ?Next matchVancouver Whitecaps – DC UnitedSep 27, 02:30 AM WWinSporting Kansas City 0–3 Vancouver WhitecapsAug 30, 12:30 AM LLossVancouver Whitecaps 1–3 St. Louis CitySep 06, 02:30 AM WWinVancouver Whitecaps 3–0 Los Angeles GalaxySep 10, 02:30 AM LLossVancouver Whitecaps 1–2 AustinSep 13, 10:30 PM WWinReal Salt Lake 0–3 Vancouver WhitecapsSep 20, 01:30 AM |
| 9 |  New England Revolution | 15 | 7 | 3 | 5 | 25:20 | +5 | 24 | ?Next matchReal Salt Lake – New England RevolutionSep 27, 01:30 AM WWinColumbus Crew 1–3 New England RevolutionAug 30, 08:30 PM LLossLos Angeles Galaxy 2–1 New England RevolutionSep 06, 01:30 AM WWinNew York City FC 1–2 New England RevolutionSep 10, 12:00 AM WWinChicago Fire 1–2 New England RevolutionSep 13, 09:30 PM WWinNew England Revolution 4–2 Orlando City SCSep 19, 11:30 PM |
| 10 |  Orlando City SC | 15 | 7 | 3 | 5 | 30:28 | +2 | 24 | ?Next matchPhiladelphia Union – Orlando City SCSep 26, 11:30 PM DDrawMinnesota United FC 3–3 Orlando City SCAug 30, 12:30 AM WWinOrlando City SC 1–0 San DiegoSep 05, 11:30 PM WWinAtlanta United FC 2–3 Orlando City SCSep 09, 11:30 PM WWinOrlando City SC 3–0 Toronto FCSep 12, 11:30 PM LLossNew England Revolution 4–2 Orlando City SCSep 19, 11:30 PM |
| 11 |  Colorado Rapids | 15 | 7 | 2 | 6 | 14:16 | -2 | 23 | ?Next matchLos Angeles Galaxy – Colorado RapidsSep 27, 02:30 AM WWinColorado Rapids 1–0 Real Salt LakeAug 30, 01:30 AM LLossColumbus Crew 3–0 Colorado RapidsSep 05, 11:30 PM DDrawAustin 1–1 Colorado RapidsSep 10, 12:30 AM WWinColorado Rapids 1–0 CF MontrealSep 13, 01:30 AM DDrawColorado Rapids 3–3 Seattle SoundersSep 20, 01:30 AM |
| 12 |  Chicago Fire | 15 | 6 | 4 | 5 | 26:27 | -1 | 22 | ?Next matchCharlotte – Chicago FireSep 26, 11:30 PM DDrawSeattle Sounders 2–2 Chicago FireAug 29, 08:30 PM DDrawToronto FC 4–4 Chicago FireSep 05, 11:30 PM DDrawChicago Fire 1–1 Inter MiamiSep 10, 12:30 AM LLossChicago Fire 1–2 New England RevolutionSep 13, 09:30 PM LLossNashville SC 3–0 Chicago FireSep 20, 01:30 AM |
| 13 |  FC Cincinnati | 15 | 5 | 6 | 4 | 35:38 | -3 | 21 | ?Next matchCF Montreal – FC CincinnatiSep 26, 11:30 PM DDrawFC Cincinnati 1–1 Seattle SoundersAug 22, 11:30 PM LLossNashville SC 4–0 FC CincinnatiAug 30, 12:30 AM LLossPhiladelphia Union 5–0 FC CincinnatiSep 09, 11:45 PM DDrawFC Cincinnati 3–3 CharlotteSep 12, 11:30 PM DDrawHouston Dynamo 2–2 FC CincinnatiSep 20, 12:30 AM |
| 14 |  New York Red Bulls | 15 | 6 | 3 | 6 | 18:21 | -3 | 21 | ?Next matchNew York Red Bulls – St. Louis CitySep 26, 11:30 PM LLossNew York Red Bulls 1–3 Philadelphia UnionAug 29, 11:30 PM DDrawSeattle Sounders 0–0 New York Red BullsSep 06, 12:30 AM LLossLos Angeles FC 2–0 New York Red BullsSep 10, 02:30 AM WWinColumbus Crew 0–1 New York Red BullsSep 12, 11:30 PM WWinNew York City FC 0–1 New York Red BullsSep 18, 11:30 PM |
| 15 |  Los Angeles FC | 15 | 5 | 5 | 5 | 23:17 | +6 | 20 | ?Next matchFC Dallas – Los Angeles FCSep 27, 12:30 AM DDrawDC United 0–0 Los Angeles FCAug 29, 11:30 PM DDrawReal Salt Lake 2–2 Los Angeles FCSep 06, 01:30 AM WWinLos Angeles FC 2–0 New York Red BullsSep 10, 02:30 AM LLossSporting Kansas City 3–1 Los Angeles FCSep 13, 12:30 AM DDrawSan Jose Earthquakes 2–2 Los Angeles FCSep 19, 11:30 PM |
| 16 |  New York City FC | 15 | 5 | 5 | 5 | 20:16 | +4 | 20 | ?Next matchAtlanta United FC – New York City FCSep 26, 11:30 PM DDrawToronto FC 1–1 New York City FCAug 29, 11:30 PM DDrawNew York City FC 0–0 Nashville SCSep 04, 11:30 PM LLossNew York City FC 1–2 New England RevolutionSep 10, 12:00 AM WWinReal Salt Lake 0–2 New York City FCSep 13, 01:30 AM LLossNew York City FC 0–1 New York Red BullsSep 18, 11:30 PM |
| 17 |  Portland Timbers | 15 | 5 | 4 | 6 | 28:27 | +1 | 19 | ?Next matchSan Jose Earthquakes – Portland TimbersSep 27, 02:30 AM LLossPortland Timbers 1–2 AustinAug 30, 02:30 AM WWinPortland Timbers 5–4 Minnesota United FCSep 06, 02:30 AM DDrawPortland Timbers 2–2 St. Louis CitySep 10, 02:30 AM LLossFC Dallas 2–1 Portland TimbersSep 13, 12:30 AM LLossPortland Timbers 0–1 Atlanta United FCSep 20, 02:30 AM |
| 18 |  San Diego | 15 | 5 | 4 | 6 | 25:25 | 0 | 19 | ?Next matchAustin – San DiegoSep 27, 12:30 AM WWinSan Diego 3–1 Los Angeles GalaxyAug 30, 02:30 AM LLossOrlando City SC 1–0 San DiegoSep 05, 11:30 PM LLossSan Diego 2–3 San Jose EarthquakesSep 10, 02:30 AM LLossSan Diego 0–5 Philadelphia UnionSep 14, 01:00 AM DDrawInter Miami 2–2 San DiegoSep 20, 11:00 PM |
| 19 |  DC United | 15 | 3 | 8 | 4 | 20:24 | -4 | 17 | ?Next matchVancouver Whitecaps – DC UnitedSep 27, 02:30 AM LLossCharlotte 3–1 DC UnitedAug 22, 11:30 PM DDrawDC United 0–0 Los Angeles FCAug 29, 11:30 PM WWinDC United 2–1 Columbus CrewSep 09, 11:30 PM DDrawDC United 0–0 Atlanta United FCSep 12, 11:30 PM LLossDC United 1–2 CharlotteSep 19, 11:30 PM |
| 20 |  Los Angeles Galaxy | 15 | 4 | 5 | 6 | 16:24 | -8 | 17 | ?Next matchLos Angeles Galaxy – Colorado RapidsSep 27, 02:30 AM LLossSan Diego 3–1 Los Angeles GalaxyAug 30, 02:30 AM WWinLos Angeles Galaxy 2–1 New England RevolutionSep 06, 01:30 AM LLossVancouver Whitecaps 3–0 Los Angeles GalaxySep 10, 02:30 AM DDrawLos Angeles Galaxy 1–1 Seattle SoundersSep 13, 02:30 AM WWinMinnesota United FC 2–3 Los Angeles GalaxySep 20, 12:30 AM |
| 21 |  Austin | 15 | 4 | 5 | 6 | 16:25 | -9 | 17 | ?Next matchAustin – San DiegoSep 27, 12:30 AM WWinPortland Timbers 1–2 AustinAug 30, 02:30 AM DDrawAustin 1–1 San Jose EarthquakesSep 06, 12:30 AM DDrawAustin 1–1 Colorado RapidsSep 10, 12:30 AM WWinVancouver Whitecaps 1–2 AustinSep 13, 10:30 PM DDrawFC Dallas 0–0 AustinSep 20, 12:30 AM |
| 22 |  Atlanta United FC | 15 | 4 | 4 | 7 | 18:25 | -7 | 16 | ?Next matchAtlanta United FC – New York City FCSep 26, 11:30 PM LLossAtlanta United FC 0–2 CharlotteAug 29, 11:30 PM DDrawInter Miami 2–2 Atlanta United FCSep 05, 11:30 PM LLossAtlanta United FC 2–3 Orlando City SCSep 09, 11:30 PM DDrawDC United 0–0 Atlanta United FCSep 12, 11:30 PM WWinPortland Timbers 0–1 Atlanta United FCSep 20, 02:30 AM |
| 23 |  Toronto FC | 15 | 3 | 6 | 6 | 21:29 | -8 | 15 | ?Next matchNashville SC – Toronto FCSep 27, 12:30 AM DDrawToronto FC 1–1 New York City FCAug 29, 11:30 PM DDrawToronto FC 4–4 Chicago FireSep 05, 11:30 PM WWinToronto FC 2–1 Nashville SCSep 09, 11:30 PM LLossOrlando City SC 3–0 Toronto FCSep 12, 11:30 PM LLossSt. Louis City 3–1 Toronto FCSep 20, 12:30 AM |
| 24 |  Columbus Crew | 15 | 4 | 2 | 9 | 21:26 | -5 | 14 | ?Next matchColumbus Crew – Inter MiamiSep 27, 11:00 PM LLossColumbus Crew 1–3 New England RevolutionAug 30, 08:30 PM WWinColumbus Crew 3–0 Colorado RapidsSep 05, 11:30 PM LLossDC United 2–1 Columbus CrewSep 09, 11:30 PM LLossColumbus Crew 0–1 New York Red BullsSep 12, 11:30 PM WWinCF Montreal 0–2 Columbus CrewSep 19, 11:30 PM |
| 25 |  San Jose Earthquakes | 15 | 3 | 5 | 7 | 20:31 | -11 | 14 | ?Next matchSan Jose Earthquakes – Portland TimbersSep 27, 02:30 AM DDrawHouston Dynamo 0–0 San Jose EarthquakesAug 30, 12:30 AM DDrawAustin 1–1 San Jose EarthquakesSep 06, 12:30 AM WWinSan Diego 2–3 San Jose EarthquakesSep 10, 02:30 AM WWinSan Jose Earthquakes 1–0 Houston DynamoSep 13, 02:30 AM DDrawSan Jose Earthquakes 2–2 Los Angeles FCSep 19, 11:30 PM |
| 26 |  Sporting Kansas City | 15 | 4 | 1 | 10 | 21:37 | -16 | 13 | ?Next matchHouston Dynamo – Sporting Kansas CitySep 27, 12:30 AM LLossAtlanta United FC 2–1 Sporting Kansas CityAug 23, 11:00 PM LLossSporting Kansas City 0–3 Vancouver WhitecapsAug 30, 12:30 AM LLossFC Dallas 4–3 Sporting Kansas CitySep 06, 12:30 AM WWinSporting Kansas City 3–1 Los Angeles FCSep 13, 12:30 AM LLossSporting Kansas City 3–4 Philadelphia UnionSep 20, 12:30 AM |
| 27 |  Real Salt Lake | 15 | 2 | 4 | 9 | 18:28 | -10 | 10 | ?Next matchSeattle Sounders – Real Salt LakeSep 24, 01:30 AM LLossColorado Rapids 1–0 Real Salt LakeAug 30, 01:30 AM DDrawReal Salt Lake 2–2 Los Angeles FCSep 06, 01:30 AM LLossHouston Dynamo 2–1 Real Salt LakeSep 10, 12:30 AM LLossReal Salt Lake 0–2 New York City FCSep 13, 01:30 AM LLossReal Salt Lake 0–3 Vancouver WhitecapsSep 20, 01:30 AM |
| 28 |  Minnesota United FC | 15 | 1 | 6 | 8 | 25:30 | -5 | 9 | ?Next matchSeattle Sounders – Minnesota United FCSep 27, 12:30 AM DDrawMinnesota United FC 3–3 Orlando City SCAug 30, 12:30 AM LLossPortland Timbers 5–4 Minnesota United FCSep 06, 02:30 AM LLossMinnesota United FC 1–2 FC DallasSep 10, 12:30 AM LLossSt. Louis City 4–2 Minnesota United FCSep 13, 12:30 AM LLossMinnesota United FC 2–3 Los Angeles GalaxySep 20, 12:30 AM |
| 29 |  Seattle Sounders | 15 | 1 | 6 | 8 | 15:28 | -13 | 9 | ?Next matchSeattle Sounders – Real Salt LakeSep 24, 01:30 AM DDrawFC Cincinnati 1–1 Seattle SoundersAug 22, 11:30 PM DDrawSeattle Sounders 2–2 Chicago FireAug 29, 08:30 PM DDrawSeattle Sounders 0–0 New York Red BullsSep 06, 12:30 AM DDrawLos Angeles Galaxy 1–1 Seattle SoundersSep 13, 02:30 AM DDrawColorado Rapids 3–3 Seattle SoundersSep 20, 01:30 AM |
| 30 |  CF Montreal | 15 | 1 | 6 | 8 | 15:30 | -15 | 9 | ?Next matchCF Montreal – FC CincinnatiSep 26, 11:30 PM LLossInter Miami 7–1 CF MontrealAug 29, 11:30 PM LLossPhiladelphia Union 2–0 CF MontrealSep 05, 11:30 PM LLossCF Montreal 1–2 CharlotteSep 09, 11:30 PM LLossColorado Rapids 1–0 CF MontrealSep 13, 01:30 AM LLossCF Montreal 0–2 Columbus CrewSep 19, 11:30 PM |
